bloodjourГематология и трансфузиологияRussian journal of hematology and transfusiology0234-57302411-3042ООО Издательский дом «Практика»10.35754/0234-5730-2025-70-1-62-84bloodjour-609Research ArticleОБЗОРЫREVIEWSСухая плазма: вперед в прошлоеDried plasma: Ahead to the pasthttps://orcid.org/0000-0001-8818-8949ГалстянГ. М.GalstyanG. M.

Галстян Геннадий Мартинович, доктор медицинских наук, заведующий отделением реанимации и интенсивной терапии

125167, г. Москва

Gennadiy M. Galstyan, Dr. Sci. (Med.), Head of the Resuscitation and Intensive Care Department

125167, Moscow

gengalst@gmail.comhttps://orcid.org/0000-0001-8213-1810БерковскийА. Л.BerkovskiyA. L.

Берковский Арон Леонидович, кандидат биологических наук, директор

125212, г. Москва

Aron L. Berkovskii, Cand. Sci. (Biol.), Head

125212, Moscow

aron_56@mail.ruhttps://orcid.org/0000-0002-4452-7862ВысочинИ. В.VysochinI. V.

Высочин Игорь Валерьевич, кандидат медицинских наук, заведующий кабинетом трансфузиологии

141009, Московская область, г. Мытищи

Igor V. Vysochin, Cand. Sci. (Med.), Head of the transfusion department

141009, Moscow region, Mytishchi

i.vysochin@yandex.ruhttps://orcid.org/0009-0009-2666-1046СаркисовА. И.SarkisovA. I.

Саркисов Артур Игоревич, кандидат технических наук, заместитель генерального директора

123181, г. Москва

Artur I Sarkisov, Cand. Sci. (Tech.), Deputy

123181, Moscow

gemospf@gmail.comФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской ФедерацииРоссияNational Medical Research Center for HematologyRussian FederationНПО «Ренам» МБООИ «Общество больных гемофилией»РоссияSPD Renam, Society for Persons with HemophiliaRussian FederationГБУЗ Московской области «Научно-исследовательский клинический институт детства Минздрава Московской областиРоссияResearch Clinical Institute of Childhood of the Moscow RegionRussian FederationООО «Научно-производственное предприятие Биотех-М»РоссияBiotech-M Co. Ltd.Russian Federation2025130320257016284Copyright © Галстян Г.М., Берковский А.Л., Высочин И.В., Саркисов А.И., 20252025Галстян Г.М., Берковский А.Л., Высочин И.В., Саркисов А.И.Galstyan G.M., Berkovskiy A.L., Vysochin I.V., Sarkisov A.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.htjournal.ru/jour/article/view/609Введение

Введение. Сухая плазма применяется уже более 80 лет. За это время отношение к ней менялось — от широкого признания во время Второй мировой войны до полного запрета в послевоенном периоде и возобновления производства в последние годы.

Цель

Цель: анализ данных литературы о производстве, безопасности, качестве, хранении и клинической эффективности сухой плазмы.

Основные сведения

Основные сведения. Приводится историческая справка применения сухой плазмы, анализируется состав сухой плазмы в зависимости от метода производства, регидратации, длительности хранения и редукции патогенов. Приводятся сведения о клиническом применении и эффективности сухой плазмы, в том числе концентрированной сухой плазмы.

Introduction

Introduction. Dried plasma has been used for more than 80 years. During this time the attitude to it has changed — from wide acceptance during the Second World War, to a complete ban in the post-war period and the resumption of production in recent years.

Aim

Aim: to analyze literature data on the production, safety, quality, storage and clinical efficacy of dried plasma.

Main findings

Main findings. A history of the use of dried plasma is provided; the composition of dry plasma is analyzed depending on the production method, rehydration, storage duration and pathogen reduction. Information is provided on the clinical use and effectiveness of dry plasma, including concentrated dried plasma.

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The authors declare that there are no conflicts of interest present.