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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bloodjour</journal-id><journal-title-group><journal-title xml:lang="ru">Гематология и трансфузиология</journal-title><trans-title-group xml:lang="en"><trans-title>Russian journal of hematology and transfusiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0234-5730</issn><issn pub-type="epub">2411-3042</issn><publisher><publisher-name>ООО Издательский дом «Практика»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35754/0234-5730-2026-71-1-60-74</article-id><article-id custom-type="elpub" pub-id-type="custom">bloodjour-728</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Хронический кожный зуд как психосоматический феномен при первичных кожных T-клеточных лимфомах</article-title><trans-title-group xml:lang="en"><trans-title>Chronic Pruritus as a Psychosomatic Phenomenon in Primary Cutaneous T-cell Lymphomas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7506-4947</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Выборных</surname><given-names>Д. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Vybornykh</surname><given-names>D. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Выборных Дмитрий Эдуардович, доктор медицинских наук, заведующий лабораторией по изучению психических и неврологических расстройств при заболеваниях системы крови </p><p>125167, г. Москва</p></bio><bio xml:lang="en"><p>Dmitry E. Vybornykh, Dr. Sci. (Med.) Head of the Laboratory for the Study of Mental and Neurological Disorders in Diseases of the Blood System</p><p>125167, Moscow </p></bio><email xlink:type="simple">dvyb@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3967-9183</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горенкова</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorenkova</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Горенкова Лилия Гамилевна, кандидат медицинских наук, заведующая отделением гематологии и химиотерапии острых лейкозов и лимфом с блоком трансплантации костного мозга и гемопоэтических стволовых клеток</p><p>125167, г. Москва</p></bio><bio xml:lang="en"><p>Liliya G Gorenkova, Cand. Sci. (Med.), Head of the Department of Hematology and Chemotherapy of Acute Leukemia and Lymphoma with the Bone Marrow and Hematopoietic Stem Cell Transplantation Unit</p><p>125167, Moscow </p></bio><email xlink:type="simple">l.aitova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1822-8973</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романов Дмитрий Владимирович, доктор медицинских наук, доцент, заведующий отделом клинической эпидемиологии; профессор кафедры психиатрии, психотерапии и психосоматики ИКМ</p><p>115522, г. Москва </p><p>119991, г. Москва </p></bio><bio xml:lang="en"><p>Dmitry V. Romanov, Dr. Sci. (Med.) Associate Professor, Head of the Department of Clinical Epidemiology; Professor of the Department of Psychiatry, Psychotherapy and Psychosomatics, ICM</p><p>115522, Moscow </p><p>119991, Moscow </p></bio><email xlink:type="simple">newt777@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7253-5694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Есина</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Esina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Есина Любовь Викторовна, медицинский психолог лаборатории по изучению психических и неврологических расстройств при заболеваниях системы крови; ассистент кафедры педагогики и медицинской психологии</p><p>125167, г. Москва </p><p>119991, г. Москва </p></bio><bio xml:lang="en"><p>Liubov V. Esina, medical psychologist of the Laboratory for the Study of Mental and Neurological Disorders in Diseases of the Blood System; assistant of the Department of Pedagogy and Medical Psychology</p><p>125167, Moscow </p><p>119991, Moscow </p></bio><email xlink:type="simple">esina.lv@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2985-5729</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миченко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Michenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Миченко Анна Валентиновна, кандидат медицинских наук, доцент кафедры дерматовенерологии и косметологии :  дерматовенеролог; врач-дерматовенеролог </p><p>121359, г. Москва </p><p>119192, г. Москва </p><p>107031, г. Москва </p><p>105066, г. Москва </p></bio><bio xml:lang="en"><p>Anna V. Michenko, Cand. Sci. (Med.), Associate Professor of the Department of Dermatovenereology and Cosmetology; dermatovenereologist</p><p>121359, Moscow </p><p>119192, Moscow </p><p>107031, Moscow </p><p>105066, Moscow </p></bio><email xlink:type="simple">amichenko@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8044-598X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чабаева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chabaeva</surname><given-names>Y. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чабаева Юлия Александровна, кандидат технических наук, заместитель начальника информационно-аналитического отдела</p><p>125167, г. Москва </p></bio><bio xml:lang="en"><p>Yulia A. Chabaeva, Cand. Sci. (Tech), Deputy Head of the Informational Analytical Department</p><p>125167, Moscow </p></bio><email xlink:type="simple">chabaeva.y@blood.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6288-7570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликов Сергей Михайлович, кандидат технических наук, начальник информационно-аналитического отдела </p><p>125167, г. Москва </p></bio><bio xml:lang="en"><p>Sergey M. Kulikov, Cand. Sci. (Tech.), Head of the Informational Analytical Department</p><p>125167, Moscow </p></bio><email xlink:type="simple">kulikov.s@blood.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Hematology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Научный центр психического здоровья» (ФГБНУ «НЦПЗ») ; ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center for Mental Health (NCMH) ;  I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской Федерации ; ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Hematology ; I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации ;  Медицинский научно-образовательный центр ФГБОУ ВО «Московский государственный университет им. М. В. Ломоносова» ; Международный институт психосоматического здоровья ; Институт пластической хирургии и косметологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Administrative Department of the President of the Russian Federation ; Medical Scientific and Educational Center of Moscow State University named after M.V. Lomonosov ; International Institute of Psychosomatic Health ; Institute of Plastic Surgery and Cosmetology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>07</day><month>04</month><year>2026</year></pub-date><volume>71</volume><issue>1</issue><fpage>60</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Выборных Д.Э., Горенкова Л.Г., Романов Д.В., Есина Л.В., Миченко А.В., Чабаева Ю.А., Куликов С.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Выборных Д.Э., Горенкова Л.Г., Романов Д.В., Есина Л.В., Миченко А.В., Чабаева Ю.А., Куликов С.М.</copyright-holder><copyright-holder xml:lang="en">Vybornykh D.E., Gorenkova L.G., Romanov D.V., Esina L.V., Michenko A.V., Chabaeva Y.A., Kulikov S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.htjournal.ru/jour/article/view/728">https://www.htjournal.ru/jour/article/view/728</self-uri><abstract><sec><title>Введение</title><p>Введение. Хронический кожный зуд (ХКЗ) является одним из симптомов кожных Т-клеточных лимфом (КТКЛ), который существенно снижает качество жизни больных.</p></sec><sec><title>Цель</title><p>Цель: определить факторы, ассоциированные с ХКЗ, и описать фенотипы ХКЗ у больных КТКЛ.</p></sec><sec><title>Методы</title><p>Методы. Обследованы 58 больных КТКЛ. Применяли психиатрическое интервью по МКБ-10 и психометрические шкалы: эппендорфский опросник зуда, шкалу тревоги и депрессии Бека, торонтскую шкалу алекситимии, симптоматический опросник «SCL-90-R».</p></sec><sec><title>Результаты</title><p>Результаты. ХКЗ отмечен у 84,5 % больных, его выраженность коррелировала со стадией лимфомы и депрессивной симптоматикой (p &lt; 0,05). У 39,7 % больных диагностировали аффективные и когнитивные психические расстройства. Пол, возраст и образование не влияли на наличие ХКЗ. Длительность КТКЛ была больше у больных без ХКЗ. У 58,8 % больных ХКЗ сопровождался чувством удовольствия при расчесах, у трети отмечалась формикация у и половины — социофобия, связанная с чувством стыда и самостигматизацией.</p></sec><sec><title>Заключение</title><p>Заключение. ХКЗ при КТКЛ представляет собой дерматологический и психонейроиммунный феномен. Лечение должно включать психиатрическую оценку, коррекцию депрессии и тревоги и психотерапевтическую поддержку.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Chronic pruritus (CP) is one of the symptoms of cutaneous T-cell lymphomas (CTCL), which significantly reduces the quality of life of patients.</p></sec><sec><title>Aim</title><p>Aim: to identify the factors associated with CP and describe the phenotypes of CP in patients with CTCL to determine the factors associated with CP and describe the phenotypes of CP in patients with CTCL.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. A total of 58 CTCL patients were examined. The assessment included psychiatric evaluation according to ICD-10 and psychometric instruments: the Eppendorf Itch Questionnaire, Beck Anxiety and Depression Inventories, Toronto Alexithymia Scale (TAS-26), and Symptom Checklist-90-R (SCL-90-R).</p></sec><sec><title>Results</title><p>Results. CP was found in 84.5 % of patients. CP severity correlated with lymphoma stage and depressive symptoms (p &lt; 0.05). Psychiatric disorders were diagnosed in 39.7 %, mainly affective and cognitive. Gender, age, and education had no effect on itch occurrence, whereas longer disease duration was observed in patients without CP. In 58.8 % of cases, CP was accompanied by pleasure during scratching, indicating ambivalent affective regulation. One-third of patients exhibited formication phenomena, and almost half showed social phobia associated with shame and self-stigmatization due to visible skin lesions.</p></sec><sec><title>Conclusion</title><p>Conclusion. CP in CTCL patients is a dermatological and psychoneuroimmune phenomenon Treatment should include psychiatric evaluation, correction of depression and anxiety, and psychotherapeutic support.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>кожные Т-клеточные лимфомы</kwd><kwd>хронический кожный зуд</kwd><kwd>аддиктивное развитие</kwd><kwd>психические расстройства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cutaneous T-cell lymphomas</kwd><kwd>chronic pruritus</kwd><kwd>addictive development</kwd><kwd>mental disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rowe B., Yosipovitch G. Malignancy-associated pruritus. 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