Experience of implementing a system of qualification plasma for fractionation donors
https://doi.org/10.18821/0234-5730-2016-61-2-87-91
Abstract
The rate of the detection of the markers of the Hepatitis B virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency Virus 1 and 2 types (HIV-1/HIV-2) among donors of plasma for fractionation over the period of 2012--2013 was evaluated. The incidence rate of markers of hemotransmissible infections (HTI) among donors of plasma for fractionation amounted for HIV-1/HIV-2: 0.03–0.07%, for HBV: 0.15–0.21% and for HCV: 0.35–0.37%. These indices are 1.5–2 times lower than the all-Russian indices, obtained from the results of activity of the blood service in 2012 and2013. Inthe group of "approved donors" markers of HIV-1/HIV-2, HBV and HCV were detected significantly less often (more than 10, 20 and 23 times, respectively) than among potential plasma donors. There was performed an epidemiological evaluation of the population of donors of plasma for fractionation in conformity with the standards of Plasma Protein Therapeutics Association (PPTA). The data obtained testify to the efficiency of the introduced system of qualification of donors of plasma for fractionation. The introduced system provided a level of infectious safety of stored plasma complying with international industry standards of quality – PPTA.
About the Authors
I. V. Paramonov
Kirov Scientifc-Research Institute of Hematology and Blood Transfusion;
Russian Medical Research and Production Center "Rosplazma"
Russian Federation
Russian Federation
Kirov, 610027;
Kirov, 610002
A. L. Poptsov
Russian Medical Research and Production Center "Rosplazma"
Russian Federation
Russian Federation
Poptsov Aleksandr L., head of the laboratory quality control
Kirov, 610002
A. V. Rylov
Kirov Scientifc-Research Institute of Hematology and Blood Transfusion
Russian Federation
Russian Federation
Kirov, 610027
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Review
For citations:
Paramonov I.V., Poptsov A.L., Rylov A.V. Experience of implementing a system of qualification plasma for fractionation donors. Russian journal of hematology and transfusiology. 2016;61(2):87-91. (In Russ.) https://doi.org/10.18821/0234-5730-2016-61-2-87-91
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