A new HLA-A allele, A*24:314, identified in the populations of the North Caucasus
https://doi.org/10.18821/0234-5730-2016-61-2-96-100
Abstract
Sequence based typing was used to identify human leukocyte antigen HLA-A, HLA-B, HLA-C, HLA-DRB1, HLADQB1 alleles from 2444 donors residing in the Chechen Republic and the Republic of Dagestan, Russia, for unrelated hematopoietic stem cell registry. During the performance of the research in the study population there was identified new allele, which was not previously registered on The WHO Nomenclature Committee for Factors of the HLA System. In this population, 51 HLA-A alleles from 19 groups of alleles were detected. Alleles occurred with the frequency more than 10% included HLA-A*02:01 (32.28%), 01:01 (11.54%), 24:02 (10.84%). New identified allele HLA-A*24:314 (0.31%) ranks second in the frequency of alleles among the allelic group A*24, after allele A*24:02.
About the Authors
M. A. Loginova
Russian Medical Research and Production Center "Rosplazma";
Kirov Research Institute of Hematology and Blood Transfusion
Russian Federation
Russian Federation
Loginova Mariya A., BD, PhD, head of the Department of donor of hematopoietic stem cells “Rosplasma”
Kirov, 610002;
Kirov, 610027
I. V. Paramonov
Kirov Research Institute of Hematology and Blood Transfusion
Russian Federation
Russian Federation
Kirov, 610027
Z. M. Tataeva
Republican Blood Transfusion Station of the Ministry of Health of the Chechen Republic
Russian Federation
Grozny,364037
Russian Federation
Grozny,364037
A. I. Kabardieva
Republican Blood Transfusion Station of the Ministry of Health of the Republic of Dagestan
Russian Federation
Makhachkala, 367008
Russian Federation
Makhachkala, 367008
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Review
For citations:
Loginova M.A., Paramonov I.V., Tataeva Z.M., Kabardieva A.I. A new HLA-A allele, A*24:314, identified in the populations of the North Caucasus. Russian journal of hematology and transfusiology. 2016;61(2):96-100. (In Russ.) https://doi.org/10.18821/0234-5730-2016-61-2-96-100
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