Prevention of ischemic stroke in patients with myeloproliferative neoplasms
https://doi.org/10.35754/0234-5730-2024-69-2-190-199
Abstract
Introduction. Myeloproliferative neoplasms (MPNs) are a rare but significant cause of strokes.
Aim. To describe risk factors for stroke development, as well as prevention strategies based on available literature data on patients with MPN.
Main findings. Online databases (PubMed, E-Library) were searched for studies on cerebral thrombotic complications in the setting of myeloproliferative disorders. Induction of specific cytoreductive treatment with low doses of acetylsalicylic ac id should be considered as a mandatory component of secondary prevention of noncardioembolic stroke.
About the Authors
P. I. KuznetsovaRussian Federation
Polina I. Kuznetsova, Cand. Sci. (Med.), researcher, neurologist, 1st neurological department
125367, Moscow
A. L. Melikyan
Russian Federation
Anait L. Melikyan, Dr. Sci. (Med.), head of the department of standardization and treatment methods
125167, Moscow
I. N. Subortseva
Russian Federation
Irina N. Subortseva, Cand. Sci. (Med.), researcher, hematologist, department of standardization and treatment methods
125167, Moscow
A. A. Raskurazhev
Russian Federation
Anton A. Raskurazhev, Cand. Sci. (Med.), researcher, neurologist, 1st neurological department
125367, Moscow
M. M. Tanashyan
Russian Federation
Marine M. Tanashyan, Dr. Sci. (Med.), Professor, Corr. Member of the RAS, Deputy director for science, Head of the 1st neurological department
125367, Moscow
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Review
For citations:
Kuznetsova P.I., Melikyan A.L., Subortseva I.N., Raskurazhev A.A., Tanashyan M.M. Prevention of ischemic stroke in patients with myeloproliferative neoplasms. Russian journal of hematology and transfusiology. 2024;69(2):190-199. (In Russ.) https://doi.org/10.35754/0234-5730-2024-69-2-190-199