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Prevention of ischemic stroke in patients with myeloproliferative neoplasms

https://doi.org/10.35754/0234-5730-2024-69-2-190-199

Abstract

Introduction.  Myeloproliferative neoplasms (MPNs) are a rare but significant cause of strokes.

Aim. To describe risk factors for stroke development, as well as  prevention strategies based on available literature data on patients with MPN.

Main findings.  Online databases (PubMed, E-Library) were searched for studies on cerebral thrombotic complications in the setting of myeloproliferative disorders. Induction of specific cytoreductive treatment with  low doses of acetylsalicylic ac id should be considered as a mandatory component of secondary prevention of noncardioembolic stroke.

About the Authors

P. I. Kuznetsova
Research Center of Neurology
Russian Federation

Polina I. Kuznetsova, Cand. Sci. (Med.), researcher, neurologist, 1st neurological department

125367, Moscow



A. L. Melikyan
National Medical Research Center for Hematology
Russian Federation

Anait L. Melikyan, Dr. Sci. (Med.), head of the department of standardization and treatment methods

125167, Moscow



I. N. Subortseva
National Medical Research Center for Hematology
Russian Federation

Irina N. Subortseva,  Cand. Sci. (Med.), researcher, hematologist, department of standardization and treatment methods

125167, Moscow



A. A. Raskurazhev
Research Center of Neurology
Russian Federation

Anton A. Raskurazhev, Cand. Sci. (Med.), researcher, neurologist, 1st neurological department

125367, Moscow



M. M. Tanashyan
Research Center of Neurology
Russian Federation

Marine M. Tanashyan,  Dr. Sci. (Med.), Professor, Corr. Member of the RAS, Deputy director for science, Head of the 1st neurological department

125367, Moscow



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Review

For citations:


Kuznetsova P.I., Melikyan A.L., Subortseva I.N., Raskurazhev A.A., Tanashyan M.M. Prevention of ischemic stroke in patients with myeloproliferative neoplasms. Russian journal of hematology and transfusiology. 2024;69(2):190-199. (In Russ.) https://doi.org/10.35754/0234-5730-2024-69-2-190-199

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ISSN 0234-5730 (Print)
ISSN 2411-3042 (Online)