Dried plasma: Ahead to the past
https://doi.org/10.35754/0234-5730-2025-70-1-62-84
Abstract
Introduction. Dried plasma has been used for more than 80 years. During this time the attitude to it has changed — from wide acceptance during the Second World War, to a complete ban in the post-war period and the resumption of production in recent years.
Aim: to analyze literature data on the production, safety, quality, storage and clinical efficacy of dried plasma.
Main findings. A history of the use of dried plasma is provided; the composition of dry plasma is analyzed depending on the production method, rehydration, storage duration and pathogen reduction. Information is provided on the clinical use and effectiveness of dry plasma, including concentrated dried plasma.
Keywords
dried plasma,
lyophilized plasma,
spray-dried plasma,
coagulation factors,
rehydration,
concentrated plasma
Supporting agencies: the study had no sponsorship.
About the Authors
G. M. Galstyan
National Medical Research Center for Hematology
Russian Federation
Russian Federation
Gennadiy M. Galstyan, Dr. Sci. (Med.), Head of the Resuscitation and Intensive Care Department
125167, Moscow
A. L. Berkovskiy
SPD Renam, Society for Persons with Hemophilia
Russian Federation
Russian Federation
Aron L. Berkovskii, Cand. Sci. (Biol.), Head
125212, Moscow
I. V. Vysochin
Research Clinical Institute of Childhood of the Moscow Region
Russian Federation
Russian Federation
Igor V. Vysochin, Cand. Sci. (Med.), Head of the transfusion department
141009, Moscow region, Mytishchi
A. I. Sarkisov
Biotech-M Co. Ltd.
Russian Federation
Russian Federation
Artur I Sarkisov, Cand. Sci. (Tech.), Deputy
123181, Moscow
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For citations:
Galstyan G.M., Berkovskiy A.L., Vysochin I.V., Sarkisov A.I. Dried plasma: Ahead to the past. Russian journal of hematology and transfusiology. 2025;70(1):62-84. (In Russ.) https://doi.org/10.35754/0234-5730-2025-70-1-62-84
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