Свободно циркулирующая ДНК при агрессивных зрелоклеточных В-клеточных лимфомах и лимфоме Ходжкина
https://doi.org/10.35754/0234-5730-2025-70-3-383-395
Аннотация
Введение. Изучение свободно циркулирующей ДНК (сцДНК) в плазме крови при гематологических заболеваниях вызывает все больший интерес. Накоплен значительный объем данных относительно диагностической и прогностической значимости выявления сцДНК и опухолевой сцДНК (соДНК) у онкогематологических больных.
Цель обзора литературы: анализ данных о значении выявления сцДНК при агрессивных В-клеточных лимфомах и лимфоме Ходжкина.
Основные сведения. Представлены литературные данные по изучению сцДНК, возможностей и ограничений различных методов исследования сцДНК у больных агрессивными В-клеточными лимфомами и лимфомой Ходжкина.
Об авторах
С. Ю. Смирнова
ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской Федерации
Россия
Россия
Смирнова Светлана Юрьевна, кандидат медицинских наук, гематолог клинико-диагностического отделения гематологии и химиотерапии с дневным стационаром; научный сотрудник лаборатории молекулярной гематологии
125167, г. Москва
Е. Е. Никулина
ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской Федерации
Россия
Россия
Никулина Елена Евгеньевна, научный сотрудник лаборатории молекулярной гематологии
125167, г. Москва
А. Б. Судариков
ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения Российской Федерации
Россия
Россия
Судариков Андрей Борисович, доктор биологических наук, заведующий лабораторией молекулярной гематологии
125167, г. Москва
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Рецензия
Для цитирования:
Смирнова С.Ю., Никулина Е.Е., Судариков А.Б. Свободно циркулирующая ДНК при агрессивных зрелоклеточных В-клеточных лимфомах и лимфоме Ходжкина. Гематология и трансфузиология. 2025;70(3):383-395. https://doi.org/10.35754/0234-5730-2025-70-3-383-395
For citation:
Smirnova S.Yu., Nikulina E.E., Sudarikov A.B. Cell free DNA in patient with aggressive mature cell B-cell lymphomas and Hodgkin’s lymphoma (literature review). Russian journal of hematology and transfusiology. 2025;70(3):383-395. (In Russ.) https://doi.org/10.35754/0234-5730-2025-70-3-383-395
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