The Center for Outpatient Transfusion Care is a new form of organization of specialized medical care in the field of transfusiology
https://doi.org/10.35754/0234-5730-2026-71-1-8-18
Abstract
Introduction. A system of specialized transfusiology care in a day hospital has been created in the Novosibirsk Region, the system for ensuring the immunological safety of allogeneic transfusions has been improved, and a new method for harvesting hematopoietic stem cells (HSCs) has been mastered.
Aim: to evaluate the possibility of organizing and providing specialized medical care in the field of transfusiology in a day hospital.
Material and methods. The study included the results of substitution transfusion therapy in 1,877 cases of day hospital admissions, 32,883 laboratory studies conducted in 10,276 patients who needed individual selection of RBC-containing blood components, 138 immunological studies for 28 patients with refractory transfusion who needed individual selection of platelet concentrate, 279 immunogenetic studies in 76 patients who needed selection of a compatible, HLA-gene-identical donor relative, examination of 10 HSC donors and quality control of the obtained cell products.
Results. The Outpatient Transfusion Care Center provided replacement transfusion therapy with RBC containing components to hematological and oncological patients in the amount of 6,495 doses (efficacy — 99.5 %), platelet concentrates — 986 doses (efficacy — 91.2 %); individual selection of 22,385 doses of RBC–containing blood components (99.8 % selection efficiency), individual selection of 63 doses of platelet concentrates (71.4 % selection effectiveness for individuals with HLA antibodies), selection of an HLA-identical/partially identical relative donor for 19 patients (25 % effectiveness), preparation of 10 therapeutic doses of allogeneic HSCs from healthy donors.
Conclusion. The results of the functioning and clinical effectiveness of the new form of specialized medical care in the field of transfusiology prove the possibility of providing transfusion care in out-of-hospital settings, ensuring the immunological safety of allogeneic transfusions and harvesting hematopoietic stem cells by a blood service institution.
About the Authors
Yu. V. Moore
Novosibirsk Clinical Blood Center ; Novosibirsk State Medical University
Russian Federation
Russian Federation
Yulia V. Moore, Cand. Sci. (Med.), Chief Physician; Assistant Professor at the Department of Therapy, Hematology and Transfusiology of the Faculty of Advanced Training and Vocational Training
630054, Novosibirsk
630091Novosibirsk
T. I. Pospelova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Tatyana I. Pospelova, Dr. Sci. (Med.), Vice-Rector for Research, Head of the Department of Therapy, Hematology and Transfusiology of the Faculty of Advanced Training and Vocational Training
630091Novosibirsk
K. V. Khalzov
Novosibirsk State Medical University
Russian Federation
Russian Federation
Konstantin V. Khalzov, Cand. Sci. (Med.), Assistant Professor at the Department of Therapy, Hematology and Transfusiology of the Faculty of Advanced Training and Vocational Training
630091Novosibirsk
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Review
For citations:
Moore Yu.V., Pospelova T.I., Khalzov K.V. The Center for Outpatient Transfusion Care is a new form of organization of specialized medical care in the field of transfusiology. Russian journal of hematology and transfusiology. 2026;71(1):8-18. (In Russ.) https://doi.org/10.35754/0234-5730-2026-71-1-8-18
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