ESTIMATION OF THE STATE OF METABOLIC ACTIVITY OF NEUTROPHILS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
https://doi.org/10.18821/0234-5730-2017-62-1-25-28
Abstract
The functional activity of phagocytes of peripheral blood was analyzed. 63 children with acute lymphoblastic leukemia (ALL) were included in the study. The age of the patients (36 male and 17 female) was from 1 to 14 years. All patients received chemotherapy. The control group consisted from 79 healthy children (35 male and 44 female, aged from 10 to 14 years). The effect of myelosuppression of the chemotherapy in ALL children was revealed, which was manifested as the decline of the average cytochemical coefficient under the detection of the content of cationic complex protein and the decrease of phagocytic and metabolic activity of neutrophils in the nitro blue tetrazolium test.
About the Authors
N. V. Turbasova
Tyumen State University
Russian Federation
Turbasova Natalia V., MD, PhD, Docent, Associate Professor of the Department of Human and Animals Anatomy and Physiology of Tyumen State University, Tyumen, 625043
Russian Federation
Turbasova Natalia V., MD, PhD, Docent, Associate Professor of the Department of Human and Animals Anatomy and Physiology of Tyumen State University, Tyumen, 625043
O. V. Frolova
Tyumen State University
Russian Federation
Tyumen, 625003
Russian Federation
Tyumen, 625003
V. S. Soloviev
Tyumen State University
Russian Federation
Tyumen, 625003
Russian Federation
Tyumen, 625003
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Review
For citations:
Turbasova N.V., Frolova O.V., Soloviev V.S. ESTIMATION OF THE STATE OF METABOLIC ACTIVITY OF NEUTROPHILS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA. Russian journal of hematology and transfusiology. 2017;62(1):25-28. (In Russ.) https://doi.org/10.18821/0234-5730-2017-62-1-25-28
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