The role of D-dimer in stroke risk stratification in patients with atrial fibrillation
https://doi.org/10.35754/0234-5730-2022-67-2-261-266
Abstract
Introduction. D-dimer is an important indicator, which reflects the activation of intravascular blood coagulation and fibrinolytic system. There are some data confirming that D-dimer is associated with stroke development in patients with atrial fibrillation. However, D-dimer is not included in modern stoke risk stratification scales in patients with atrial fibrillation.
Aim — to analyze the data devoted to the role of D-dimer in stroke risk stratification in patients with atrial fibrillation.
General findings. D-dimer, despite several limitations, could be used in clinical practice as an indicator that is associated with stroke development in patients with atrial fibrillation. D-dimer level estimation could help to decide whether to use anticoagulant treatment in patients with low risk of stroke development or in those patients with a single non-sex CHA2DS2-VASc score risk factor.
About the Authors
A. O. Rubanenko
Samara State Medical University
Russian Federation
Russian Federation
Anatolii O. Rubanenko — Cand. Sci. (Med.), Associate Professor at the Department of Propedeutic Therapy
443099, Samara
O. A. Rubanenko
Samara State Medical University
Russian Federation
Russian Federation
Olesya A. Rubanenko — Cand. Sci. (Med.), Associate Professor of the Department of Hospital Therapy with Courses of Polyclinic Therapy and Transfusiology
443099, Samara
V. A. Dyachkov
Samara State Medical University
Russian Federation
Russian Federation
Vladislav A. Dyachkov, Cand. Sci. (Med.), Associate Professor of the Department of Propaedeutic Therapy
443099, Samara
Yu. V. Shchukin
Samara State Medical University
Russian Federation
Russian Federation
Yuri V. Shchukin, Doct. Sci. (Med.), Professor, Head of Propaedeutic Therapy Department
443099, Samara
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Review
For citations:
Rubanenko A.O., Rubanenko O.A., Dyachkov V.A., Shchukin Yu.V. The role of D-dimer in stroke risk stratification in patients with atrial fibrillation. Russian journal of hematology and transfusiology. 2022;67(2):261-266. (In Russ.) https://doi.org/10.35754/0234-5730-2022-67-2-261-266
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