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Гематология и трансфузиология

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ПРИМЕНЕНИЕ КОНЦЕНТРАТОВ ПРОТРОМБИНОВОГО КОМПЛЕКСА ПО УТВЕРЖДЕННЫМ И НЕУТВЕРЖДЕННЫМ ПОКАЗАНИЯМ: НОВЫЕ ПЕРСПЕКТИВЫ СТАРЫХ ПРЕПАРАТОВ

https://doi.org/10.25837/HAT.2018.30..1..008

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Аннотация

Концентраты протромбинового комплекса (КПК), содержащие витамин K-зависимые факторы, были разработаны для реверсии действия антагонистов витаминов. Однако в последние годы КПК все чаще применяются по другим показаниям. Роль настоящего обзора — осветить применение КПК для лечения кровотечений при реверсии действия прямых оральных антикоагулянтов, при оперативных вмешательствах, травме, заболеваниях печени. Обсуждается также безопасность КПК.

Об авторе

Г. М. Галстян
ФГБУ «Национальный медицинский исследовательский центр гематологии» Министерства здравоохранения России, Москва
Россия
Галстян Геннадий Мартинович, доктор мед. наук, заведующий научно-клиническим отделением реанимации и интенсивной терапии ФГБУ «НМИЦ гематологии» Министерства здравоохранения России, 125167


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Для цитирования:


Галстян Г.М. ПРИМЕНЕНИЕ КОНЦЕНТРАТОВ ПРОТРОМБИНОВОГО КОМПЛЕКСА ПО УТВЕРЖДЕННЫМ И НЕУТВЕРЖДЕННЫМ ПОКАЗАНИЯМ: НОВЫЕ ПЕРСПЕКТИВЫ СТАРЫХ ПРЕПАРАТОВ. Гематология и трансфузиология. 2018;63(1):78-91. https://doi.org/10.25837/HAT.2018.30..1..008

For citation:


Galstyan G.M. LABEL AND OFF-LABEL APPLICATIONS OF PROTHROMBIN COMPLEX CONCENTRATES. NEW PERSPECTIVES OF OLD DRUGS. Russian journal of hematology and transfusiology. 2018;63(1):78-91. (In Russ.) https://doi.org/10.25837/HAT.2018.30..1..008

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