CASE OF ATYPICAL WARFARIN-INDUCED SKIN NECROSIS IN A CHILD WITH CONGENITAL HEART DISEASE
V. A. Lastovka,
R. F. Tepaev,
O. B. Gordeeva,
L. A. Gandaeva,
E. N. Basargina,
Yu. V. Derevnina,
Ye. L. Penkov https://doi.org/10.35754/0234-5730-2019-64-4-483-488
Abstract
Introduction. Warfarin-induced skin necrosis constitutes a rare complication of warfarin treatment.
Aim. To present a case study of the occurrence and successful treatment of atypical warfarin-induced skin necrosis in a child with congenital heart disease.
General findings. The development of finger skin necrosis in a child with congenital heart disease almost 2 years after the start of warfarin therapy was described. In addition, possible causes of the complication and methods for its treatment were discussed.
Conflict of interest: the authors declare no conflict of interest.
Financial disclosure: the study had no sponsorship
About the Authors
V. A. Lastovka
National Medical Research Center for Children’s Health
Russian Federation
Vasily A. Lastovka, Intensivist
Russian Federation
Vasily A. Lastovka, Intensivist
R. F. Tepaev
National Medical Research Center for Children’s Health;
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Rustem F. Tepaev, Dr. Sci. (Med.), Head of Resuscitation and Intensive Care Unit
Russian Federation
Rustem F. Tepaev, Dr. Sci. (Med.), Head of Resuscitation and Intensive Care Unit
O. B. Gordeeva
National Medical Research Center for Children’s Health
Russian Federation
Russian Federation
Olga B. Gordeeva, Cand. Sci. (Med.), Senior Researcher, Laboratory of Experimental Immunology and Virology
tel.: +7(963)782-02-06
L. A. Gandaeva
National Medical Research Center for Children’s Health
Russian Federation
Layla A. Gandaeva, Cand. Sci. (Med.), Pediatrician
Russian Federation
Layla A. Gandaeva, Cand. Sci. (Med.), Pediatrician
E. N. Basargina
National Medical Research Center for Children’s Health
Russian Federation
Elena N. Basargina, Dr. Sci. (Med.), Head of Cardiology Department
Russian Federation
Elena N. Basargina, Dr. Sci. (Med.), Head of Cardiology Department
Yu. V. Derevnina
National Medical Research Center for Children’s Health
Russian Federation
Yuliya V. Derevnina, Pediatrician
Russian Federation
Yuliya V. Derevnina, Pediatrician
Ye. L. Penkov
National Medical Research Center for Children’s Health;
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Yevgeny L. Penkov, Junior Researcher, Laboratory of Molecular Genetics and Cell Biology
Russian Federation
Yevgeny L. Penkov, Junior Researcher, Laboratory of Molecular Genetics and Cell Biology
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Review
For citations:
Lastovka V.A., Tepaev R.F., Gordeeva O.B., Gandaeva L.A., Basargina E.N., Derevnina Yu.V., Penkov Ye.L. CASE OF ATYPICAL WARFARIN-INDUCED SKIN NECROSIS IN A CHILD WITH CONGENITAL HEART DISEASE. Russian journal of hematology and transfusiology. 2019;64(4):483–488. (In Russ.) https://doi.org/10.35754/0234-5730-2019-64-4-483-488
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